Stellate DNA
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  • Gatalyst™ Donor
  • Gatalyst™ CRISPR
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Gene Editing Has Come Full Circle

Gene Editing Has Come Full CircleGene Editing Has Come Full CircleGene Editing Has Come Full Circle

 Gatalyst™ for Large CRISPR Knock-in Donors

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Gene Editing Has Come Full Circle

Gene Editing Has Come Full CircleGene Editing Has Come Full CircleGene Editing Has Come Full Circle

 Gatalyst™ for Large CRISPR Knock-in Donors

Contact Us

StEllate DNA Gatalyst™ Donors DELIVER ULTRA-LARGE PAYLOads

StellateDNA LOGO

See an overview in a short videoclip

See an overview in a short videoclip

See an overview in a short videoclip

 https://lnkd.in/g5gdg9u5 

https://www.youtube.com/watch?v=xeSsDBPPdvg&t=3s


Proprietary DNA Donor Technology

See an overview in a short videoclip

See an overview in a short videoclip

We design, produce, and deliver custom DNA donors for use as homology-directed repair (HDR) templates in genome editing. The Gatalyst™ (Genome Catalyst) technology benefits multiple aspects of gene editing and cell engineering with potential to impact diverse  markets in the life sciences.  


Ultra-large Size Payload Capacity

See an overview in a short videoclip

Ultra-large Size Payload Capacity

The Stellate DNA Gatalyst™ platform is an integrated suite of technologies to design and manufacture single-stranded DNA donors for high efficiency, low cell toxicity, large-size enabled (up to 20 kb) homology directed repair (HDR) based knock-ins of payloads using the  CRISPR-Cas9 system. 

Superior Integration Efficiency

Superior Integration Efficiency

Ultra-large Size Payload Capacity

The Stellate Gatalyst™ donor is in a circular form which minimizes the non-homologous interaction between the donor and the genome loci other than the editing target region. The circular formation also protects the donor from degradation more efficiently which ensures a longer half-life compared with the linearized single-strand donor.

Large Scale Delivery Capacity

Superior Integration Efficiency

Large Scale Delivery Capacity

The Stellate DNA Gatalyst™ platform utilizes clonal rather than chemical synthesis to manufacture the customizable gene knock-in payload which guarantees not only microgram to milligram scale production with well-controlled cost but also ensures a minimal mutation rate and sequence uniformity. 

Customizable Design Enabled

Superior Integration Efficiency

Large Scale Delivery Capacity

The Stellate DNA Gatalyst™ platform is flexible and allows you to design your preferred ssDNA donor. Gatalyst™ gene editing donors will advance the gene editing field into a high-throughput era to expedite cell engineering, animal model generation and therapeutic research. 

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