Stellate DNA
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  • Gatalyst™ Donor
  • Gatalyst™ CRISPR
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Gene Editing Has Come Full Circle

Gene Editing Has Come Full CircleGene Editing Has Come Full CircleGene Editing Has Come Full Circle

 Gatalyst™ for Large CRISPR Knock-in Donors

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Gene Editing Has Come Full Circle

Gene Editing Has Come Full CircleGene Editing Has Come Full CircleGene Editing Has Come Full Circle

 Gatalyst™ for Large CRISPR Knock-in Donors

Contact Us

StEllate DNA Gatalyst™ Donors DELIVER ULTRA-LARGE PAYLOads

StellateDNA LOGO

See an overview in a short videoclip

See an overview in a short videoclip

See an overview in a short videoclip

 https://lnkd.in/g5gdg9u5 

https://www.youtube.com/watch?v=xeSsDBPPdvg&t=3s


Ultra-large Size Payload Capacity

See an overview in a short videoclip

See an overview in a short videoclip

The Stellate DNA Gatalyst™ platform is an integrated suite of technologies to design and manufacture single-stranded DNA donors for high efficiency, low cell toxicity, large-size enabled (up to 20 kb) homology directed repair (HDR) based knock-ins of payloads using the  CRISPR-Cas9 system. 

Proprietary DNA Donor Technology

See an overview in a short videoclip

Superior Integration Efficiency

We design, produce, and deliver custom DNA donors for use as homology-directed repair (HDR) templates in genome editing. The Gatalyst™ (Genome Catalyst) technology benefits multiple aspects of gene editing and cell engineering with potential to impact diverse  markets in the life sciences.  


Superior Integration Efficiency

Superior Integration Efficiency

Superior Integration Efficiency

The Stellate Gatalyst™ donor is in a circular form which minimizes the non-homologous interaction between the donor and the genome loci other than the editing target region. The circular formation also protects the donor from degradation more efficiently which ensures a longer half-life compared with the linearized single-strand donor.

Large Scale Delivery Capacity

Superior Integration Efficiency

Large Scale Delivery Capacity

The Stellate DNA Gatalyst™ platform utilizes clonal rather than chemical synthesis to manufacture the customizable gene knock-in payload which guarantees not only microgram to milligram scale production with well-controlled cost but also ensures a minimal mutation rate and sequence uniformity. 

Customizable Design Enabled

Superior Integration Efficiency

Large Scale Delivery Capacity

The Stellate DNA Gatalyst™ platform is flexible and allows you to design your preferred ssDNA donor. Gatalyst™ gene editing donors will advance the gene editing field into a high-throughput era to expedite cell engineering, animal model generation and therapeutic research. 

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