StEllate DNA Gatalyst™ Donors DELIVER ULTRA-LARGE PAYLOads
See an overview in a short videoclip
See an overview in a short videoclip
See an overview in a short videoclip
Ultra-large Size Payload Capacity
See an overview in a short videoclip
See an overview in a short videoclip
The Stellate DNA Gatalyst™ platform is an integrated suite of technologies to design and manufacture single-stranded DNA donors for high efficiency, low cell toxicity, large-size enabled (up to 20 kb) homology directed repair (HDR) based knock-ins of payloads using the CRISPR-Cas9 system.
Proprietary DNA Donor Technology
See an overview in a short videoclip
Superior Integration Efficiency
We design, produce, and deliver custom DNA donors for use as homology-directed repair (HDR) templates in genome editing. The Gatalyst™ (Genome Catalyst) technology benefits multiple aspects of gene editing and cell engineering with potential to impact diverse markets in the life sciences.
Superior Integration Efficiency
Superior Integration Efficiency
Superior Integration Efficiency
The Stellate Gatalyst™ donor is in a circular form which minimizes the non-homologous interaction between the donor and the genome loci other than the editing target region. The circular formation also protects the donor from degradation more efficiently which ensures a longer half-life compared with the linearized single-strand donor.
Large Scale Delivery Capacity
Superior Integration Efficiency
Large Scale Delivery Capacity
The Stellate DNA Gatalyst™ platform utilizes clonal rather than chemical synthesis to manufacture the customizable gene knock-in payload which guarantees not only microgram to milligram scale production with well-controlled cost but also ensures a minimal mutation rate and sequence uniformity.
Customizable Design Enabled
Superior Integration Efficiency
Large Scale Delivery Capacity
The Stellate DNA Gatalyst™ platform is flexible and allows you to design your preferred ssDNA donor. Gatalyst™ gene editing donors will advance the gene editing field into a high-throughput era to expedite cell engineering, animal model generation and therapeutic research.